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	1. 455 Accesses	Research A multilevel layout algorithm for visualizing physical and genetic interaction networks, with emphasis on their modular organization Johannes Tuikkala, Heidi Vähämaa, Pekka Salmela, Olli S Nevalainen, Tero Aittokallio BioData Mining 2012, 5:2 (26 March 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary New multilevel network layout algorithms allow researchers to create biologically relevant and visually pleasing network graphs for large datasets within a multi optimization framework.
	2. 448 Accesses	Review Using graph theory to analyze biological networks Georgios A Pavlopoulos, Maria Secrier, Charalampos N Moschopoulos, Theodoros G Soldatos, Sophia Kossida, Jan Aerts, Reinhard Schneider, Pantelis G Bagos BioData Mining 2011, 4:10 (28 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	3. 350 Accesses	Review A reference guide for tree analysis and visualization Georgios A Pavlopoulos, Theodoros G Soldatos, Adriano Barbosa-Silva, Reinhard Schneider BioData Mining 2010, 3:1 (22 February 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	4. 272 Accesses	Review A survey of visualization tools for biological network analysis Georgios A Pavlopoulos, Anna-Lynn Wegener, Reinhard Schneider BioData Mining 2008, 1:12 (28 November 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	5. 251 Accesses	Software article Caipirini: using gene sets to rank literature Theodoros G Soldatos, Seán I O'Donoghue, Venkata P Satagopam, Adriano Barbosa-Silva, Georgios A Pavlopoulos, Ana Wanderley-Nogueira, Nina Soares-Cavalcanti, Reinhard Schneider BioData Mining 2012, 5:1 (1 February 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary 'Caipirini', a new software program, allows ranking of biomedical literature based on biological relevance to gene sets, thereby enabling data from these high-throughput experiments to be more easily accessed.
	6. 242 Accesses	Research Search extension transforms Wiki into a relational system: A case for flavonoid metabolite database Masanori Arita, Kazuhiro Suwa BioData Mining 2008, 1:7 (17 September 2008) Abstract \| Full text \| PDF \| PubMed
	7. 187 Accesses	Research Partitioning clustering algorithms for protein sequence data sets Sondes Fayech, Nadia Essoussi, Mohamed Limam BioData Mining 2009, 2:3 (2 April 2009) Abstract \| Full text \| PDF \| PubMed
	8. 183 Accesses	Research Comprehensive analysis of human microRNA target networks Jun-ichi Satoh, Hiroko Tabunoki BioData Mining 2011, 4:17 (17 June 2011) Abstract \| Full text \| PDF \| PubMed
	9. 172 Accesses	Methodology Spatially Uniform ReliefF (SURF) for computationally-efficient filtering of gene-gene interactions Casey S Greene, Nadia M Penrod, Jeff Kiralis, Jason H Moore BioData Mining 2009, 2:5 (22 September 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	10. 168 Accesses	Software article An R package implementation of multifactor dimensionality reduction Stacey J Winham, Alison A Motsinger-Reif BioData Mining 2011, 4:24 (16 August 2011) Abstract \| Full text \| PDF \| PubMed
	11. 162 Accesses	Editorial Mining the diseasome Davnah Urbach, Jason H Moore BioData Mining 2011, 4:25 (9 September 2011) Abstract \| Full text \| PDF \| PubMed
	12. 158 Accesses	Review A review of estimation of distribution algorithms in bioinformatics Rubén Armañanzas, Iñaki Inza, Roberto Santana, Yvan Saeys, Jose Flores, Jose Lozano, Yves Peer, Rosa Blanco, Víctor Robles, Concha Bielza, Pedro Larrañaga BioData Mining 2008, 1:6 (11 September 2008) Abstract \| Full text \| PDF \| PubMed
	13. 155 Accesses	Methodology Discrete derivative: a data slicing algorithm for exploration of sharing biological networks between rheumatoid arthritis and coronary heart disease Guang Zheng, Miao Jiang, Xiaojuan He, Jing Zhao, Hongtao Guo, Gao Chen, Qinglin Zha, Aiping Lu BioData Mining 2011, 4:18 (23 June 2011) Abstract \| Full text \| PDF \| PubMed
	14. 149 Accesses	Research A comparison of machine learning techniques for survival prediction in breast cancer Leonardo Vanneschi, Antonella Farinaccio, Giancarlo Mauri, Mauro Antoniotti, Paolo Provero, Mario Giacobini BioData Mining 2011, 4:12 (11 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	15. 147 Accesses	Research 3PFDB - A database of Best Representative PSSM Profiles (BRPs) of Protein Families generated using a novel data mining approach Khader Shameer, Paramasivam Nagarajan, Kumar Gaurav, Ramanathan Sowdhamini BioData Mining 2009, 2:8 (4 December 2009) Abstract \| Full text \| PDF \| PubMed
	16. 146 Accesses	Research DADA: Degree-Aware Algorithms for Network-Based Disease Gene Prioritization Sinan Erten, Gurkan Bebek, Rob M Ewing, Mehmet Koyutürk BioData Mining 2011, 4:19 (24 June 2011) Abstract \| Full text \| PDF \| PubMed
	17. 144 Accesses	Research Fast approximate hierarchical clustering using similarity heuristics Meelis Kull, Jaak Vilo BioData Mining 2008, 1:9 (22 September 2008) Abstract \| Full text \| PDF \| PubMed
	18. 134 Accesses	Software article Fast Gene Ontology based clustering for microarray experiments Kristian Ovaska, Marko Laakso, Sampsa Hautaniemi BioData Mining 2008, 1:11 (21 November 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	19. 129 Accesses	Research Database mining for selection of SNP markers useful in admixture mapping Tesfaye M Baye, Hemant K Tiwari, David B Allison, Rodney C Go BioData Mining 2009, 2:1 (14 February 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	20. 127 Accesses	Research Detection of changes in gene regulatory patterns, elicited by perturbations of the Hsp90 molecular chaperone complex, by visualizing multiple experiments with an animation Pablo C Echeverría, Fedor Forafonov, Deo P Pandey, Guillaume Mühlebach, Didier Picard BioData Mining 2011, 4:15 (14 June 2011) Abstract \| Full text \| PDF \| PubMed
	21. 126 Accesses	Review Clustering-based approaches to SAGE data mining Haiying Wang, Huiru Zheng, Francisco Azuaje BioData Mining 2008, 1:5 (17 July 2008) Abstract \| Full text \| PDF \| PubMed
	22. 123 Accesses	Methodology Statistical quality assessment and outlier detection for liquid chromatography-mass spectrometry experiments Ole Schulz-Trieglaff, Egidijus Machtejevas, Knut Reinert, Hartmut Schlüter, Joachim Thiemann, Klaus Unger BioData Mining 2009, 2:4 (7 April 2009) Abstract \| Full text \| PDF \| PubMed
	23. 120 Accesses	Research Modeling gene-by-environment interaction in comorbid depression with alcohol use disorders via an integrated bioinformatics approach Richard C McEachin, Benjamin J Keller, Erika FH Saunders, Melvin G McInnis BioData Mining 2008, 1:2 (17 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	24. 120 Accesses	Review Extraction of pure components from overlapped signals in gas chromatography-mass spectrometry (GC-MS) Vladimir A Likić BioData Mining 2009, 2:6 (12 October 2009) Abstract \| Full text \| PDF \| PubMed
	25. 117 Accesses	Research A biclustering algorithm based on a Bicluster Enumeration Tree: application to DNA microarray data Wassim Ayadi, Mourad Elloumi, Jin-Kao Hao BioData Mining 2009, 2:9 (16 December 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central